Ontology highlight
ABSTRACT:
SUBMITTER: Tasnadi G
PROVIDER: S-EPMC6174958 | biostudies-literature | 2018 Jun
REPOSITORIES: biostudies-literature
Tasnádi Gábor G Jud Wolfgang W Hall Mélanie M Baldenius Kai K Ditrich Klaus K Faber Kurt K
Advanced synthesis & catalysis 20180502 12
Undesired product hydrolysis along with large amounts of waste in form of inorganic monophosphate by-product are the main obstacles associated with the use of pyrophosphate in the phosphatase-catalyzed synthesis of phosphate monoesters on large scale. In order to overcome both limitations, we screened a broad range of natural and synthetic organic phosphate donors with several enzymes on a broad variety of hydroxyl-compounds. Among them, acetyl phosphate delivered stable product levels and high ...[more]