Ontology highlight
ABSTRACT:
SUBMITTER: Hutchings J
PROVIDER: S-EPMC6175875 | biostudies-literature | 2018 Oct
REPOSITORIES: biostudies-literature
Nature communications 20181008 1
Eukaryotic cells employ membrane-bound carriers to transport cargo between compartments in a process essential to cell functionality. Carriers are generated by coat complexes that couple cargo capture to membrane deformation. The COPII coat mediates export from the endoplasmic reticulum by assembling in inner and outer layers, yielding carriers of variable shape and size that allow secretion of thousands of diverse cargo. Despite detailed understanding of COPII subunits, the molecular mechanisms ...[more]