Ontology highlight
ABSTRACT:
SUBMITTER: Patrick MT
PROVIDER: S-EPMC6177414 | biostudies-literature | 2018 Oct
REPOSITORIES: biostudies-literature
Nature communications 20181009 1
Psoriatic arthritis (PsA) is a complex chronic musculoskeletal condition that occurs in ~30% of psoriasis patients. Currently, no systematic strategy is available that utilizes the differences in genetic architecture between PsA and cutaneous-only psoriasis (PsC) to assess PsA risk before symptoms appear. Here, we introduce a computational pipeline for predicting PsA among psoriasis patients using data from six cohorts with >7000 genotyped PsA and PsC patients. We identify 9 new loci for psorias ...[more]