A binary matrix for the rapid detection and characterization of small-molecule cardiovascular drugs by MALDI-MS and MS/MS.
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ABSTRACT:
SUBMITTER: Dong J
PROVIDER: S-EPMC6178826 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
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A binary matrix for the rapid detection and characterization of small-molecule cardiovascular drugs by MALDI-MS and MS/MS.
Dong Jinlan J Ning Wenjing W Mans Daniel J DJ Mans Jamie D JD
Analytical methods : advancing methods and applications 20180201
A mixture of α-cyano-4-hydroxycinnamic acid and 1,5-diaminonaphthalene was discovered as a novel binary matrix for the qualitative analysis of 14 small-molecule (~250-550 Da) cardiovascular drugs by matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) and MS/MS in either positive or negative ion mode. ...[more]
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