Ontology highlight
ABSTRACT:
SUBMITTER: Mayer FP
PROVIDER: S-EPMC6180071 | biostudies-literature | 2018 Nov
REPOSITORIES: biostudies-literature
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20180406 12
Amphetamine abuse is a major public health concern for which there is currently no effective treatment. To develop effective treatments, the mechanisms by which amphetamine produces its abuse-related effects need to be fully understood. It is well known that amphetamine exerts its actions by targeting high-affinity transporters for monoamines, in particular the cocaine-sensitive dopamine transporter. Organic cation transporter 3 (OCT3) has recently been found to play an important role in regulat ...[more]