Dataset Information

Risk factors of presenile nuclear cataract in health screening study.

ABSTRACT:

Background

To identify risk factors for the development of presenile nuclear cataract in health screening test.

Methods

The cross sectional study included a total of 532 eyes of 266 participants aged 30 to 49 years of Samsung Medical Center from February 2013 to April 2015. Presence of nuclear cataract was defined when the log MAR visual acuity with correction was greater than or equal to 0.2 and one or more of the following were met: Pentacam Nuclear Staging (PNS) grading score???1, average value of nuclear density???15%, maximum value of nuclear density???30%. Possible risk factors were obtained from blood tests and questionnaires of a health screening test of Samsung Medical Center. Association between nuclear cataract and risk factors was investigated using univariate and multivariate logistic regression analysis by generalized estimating equation (GEE) models.

Results

Five factors were significantly associated with presenile nuclear cataract: current smoking [odds ratio (OR)?=?2.80, 95% confidence interval (CI), 1.10-7.12, p?=?0.0310], non-exercise and high amount of daily physical exercise (OR?=?3.99, 95% CI, 1.27-12.52, p?=?0.0178; OR?=?2.92, 95% CI, 1.38-6.22, p?=?0.0053), asthma (OR?=?8.93, 95% CI, 1.12-71.15, p?=?0.0386), tuberculosis (OR?=?4.28, 95% CI, 1.36-13.50, p?=?0.0131), and higher total iron binding capacity (OR?=?1.01, 95% CI, 1.00-1.02, p?=?0.0059).

Conclusions

Presenile nuclear cataract is related to current smoking, non-exercise or high amount of physical exercise, asthma, tuberculosis, and iron deficiency status. The association of non-exercise group and presenile nuclear cataract seems to be related to co-morbidity. Patients with asthma, tuberculosis, or iron deficiency anemia are recommended to receive frequent ophthalmic examination to detect cataract.

SUBMITTER: Nam SW

PROVIDER: S-EPMC6180395 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature

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Publications

Risk factors of presenile nuclear cataract in health screening study.

Nam Seung Wan SW Lim Dong Hui DH Cho Kyu Yeon KY Kim Hye Seung HS Kim Kyunga K Chung Tae-Young TY

BMC ophthalmology 20181011 1

<h4>Background</h4>To identify risk factors for the development of presenile nuclear cataract in health screening test.<h4>Methods</h4>The cross sectional study included a total of 532 eyes of 266 participants aged 30 to 49 years of Samsung Medical Center from February 2013 to April 2015. Presence of nuclear cataract was defined when the log MAR visual acuity with correction was greater than or equal to 0.2 and one or more of the following were met: Pentacam Nuclear Staging (PNS) grading score ≥ ...[more]

PMID: 30305075

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Project description:BackgroundLike many other women in the developing world, the practice of breast cancer screening among Ghanaian women is unsatisfactory. As a result, many cases are diagnosed at advanced stages leading to poor outcomes including mortalities. An understanding of the awareness and predictors of breast examination is an important first step that may guide the design of interventions aimed at raising awareness across the general population. This study aimed to explore the awareness, risk factors, and self-reported screening practices of breast cancer among female undergraduate students at the University of Health and Allied Sciences.MethodsThis cross-sectional study was conducted among 385 female undergraduate students using a pre-tested questionnaire. Data were analysed using Stata Version 13.1 and presented using descriptive and inferential statistics comprising frequency, percentage, chi-square, and binary logistic regression. Odds ratios and 95% confidence intervals were computed to quantify the association between regular Breast-Self Examination (BSE) and socio-demographic characteristics of respondents.ResultsSeventy-three per cent of the students were aware of breast cancer, with social media being the most important source of information (64.4%). The prevalence of breast cancer risk factors varied from 1% of having a personal history of breast cancer to 14.3% for positive family history of breast cancer. Current use of oral pills/injectable contraceptives was confirmed by 13.2% of participants; 20% were current alcohol users and10.1% were physically inactive. Regarding breast examination, 42.6% performed BSE; 10.1% had Clinical Breast Examination (CBE), while 2.3% had undergone mammography in the three years preceding the study. Women who did not believe to be susceptible to breast cancer (AOR: 0.04; 95%CI: 0.02-0.09) and those who did not know their risk status (AOR: 0.02; 95%CI: 0.005-0.57) were less likely to perform regular BSE compared to those who displayed pessimism. Further, women with no religious affiliation had 0.11 (95%CI: 0.02-0.55) odds of examining their breast regularly compared to Christians.ConclusionThis study demonstrated moderate awareness of the modalities of breast cancer screening and the risk factors of breast cancer among the students. However, there exists a gap between awareness and practice of breast cancer screening, which was influenced by optimism in breast cancer risk perception and religion. Awareness campaigns and education should be intensified in the University to bridge this gap.

Dataset Information

Risk factors of presenile nuclear cataract in health screening study.

Background

Methods

Results

Conclusions

Publications

Risk factors of presenile nuclear cataract in health screening study.

Similar Datasets

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