Ontology highlight
ABSTRACT:
SUBMITTER: Kurokawa C
PROVIDER: S-EPMC6186520 | biostudies-literature | 2018 Oct
REPOSITORIES: biostudies-literature
Journal of the National Cancer Institute 20181001 10
<h4>Background</h4>Attenuated measles virus (MV) strains are promising agents currently being tested against solid tumors or hematologic malignancies in ongoing phase I and II clinical trials; factors determining oncolytic virotherapy success remain poorly understood, however.<h4>Methods</h4>We performed RNA sequencing and gene set enrichment analysis to identify pathways differentially activated in MV-resistant (n = 3) and -permissive (n = 2) tumors derived from resected human glioblastoma (GBM ...[more]