A Handy Liquid Metal Based Non-Invasive Electrophoretic Particle Microtrap.

ABSTRACT: A handy liquid metal based non-invasive particle microtrap was proposed and demonstrated in this work. This kind of microtrap can be easily designed and fabricated at any location of a microfluidic chip to perform precise particle trapping and releasing without disturbing the microchannel itself. The microsystem demonstrated in this work utilized silicon oil as the continuous phase and fluorescent particles (PE-Cy5, SPHERO^TM Fluorescent Particles, BioLegend, San Diego, CA, USA, 10.5 ?m) as the target particles. To perform the particle trapping, the micro system utilized liquid-metal-filled microchannels as noncontact electrodes to generate different patterns of electric field inside the fluid channel. According to the experimental results, the target particle can be selectively trapped and released by switching the electric field patterns. For a better understanding the control mechanism, a numerical simulation of the electric field was performed to explain the trapping mechanism. In order to verify the model, additional experiments were performed and are discussed.

SUBMITTER: Tian L 

PROVIDER: S-EPMC6187542 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature