Exercise training alters the genomic response to acute exercise in human adipose tissue.
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ABSTRACT:
SUBMITTER: Fabre O
PROVIDER: S-EPMC6190185 | biostudies-literature | 2018 Aug
REPOSITORIES: biostudies-literature
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Exercise training alters the genomic response to acute exercise in human adipose tissue.
Fabre Odile O Ingerslev Lars R LR Garde Christian C Donkin Ida I Simar David D Barrès Romain R
Epigenomics 20180419 8
<h4>Aim</h4>To determine the genomic mechanisms by which adipose tissue responds to acute and chronic exercise.<h4>Methods</h4>We profiled the transcriptomic and epigenetic response to acute exercise in human adipose tissue collected before and after endurance training.<h4>Results</h4>Although acute exercises were performed at same relative intensities, the magnitude of transcriptomic changes after acute exercise was reduced by endurance training. DNA methylation remodeling induced by acute exer ...[more]
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