A Novel Prognostic Nomogram for Predicting Risks of Distant Failure in Patients with Invasive Breast Cancer Following Postoperative Adjuvant Radiotherapy.

ABSTRACT:

Purpose

This study aimed to identify predictors for distant metastatic behavior and build a related prognostic nomogram in breast cancer.

Materials and methods

A total of 1,181 patients with non-metastatic breast cancer between 2003 and 2011 were analyzed. To predict the probability of distant metastasis, a nomogram was constructed based on prognostic factors identified using a Cox proportional hazards model.

Results

The 7-year overall survival and 5-year post-progression survival of locoregional versus distant recurrence groups were 67.6% versus 39.1% (p=0.027) and 54.2% versus 33.5% (p=0.043), respectively. Patients who developed distant metastasis showed early and late mortality risk peaks within 3 and after 5 years of follow-up, respectively, but a broad and low r

SUBMITTER: Lim YJ 

PROVIDER: S-EPMC6192903 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature