Ontology highlight
ABSTRACT:
SUBMITTER: Meng L
PROVIDER: S-EPMC6193014 | biostudies-literature | 2018 Oct
REPOSITORIES: biostudies-literature
Meng Lingjiao L Liu Fei F Ju Yingchao Y Ding Pingan P Liu Sihua S Chang Sheng S Liu Shina S Zhang Yi Y Lian Yishui Y Gu Lina L Zhang Xiaochong X Sang Meixiang M
Cell death & disease 20181017 11
Accumulating evidences indicate that microRNAs (miRNAs) play vital roles in multiple diseases, including cancer. In the present study, we showed that miR-6775-3p plays a tumor suppressive role in esophageal squamous cell carcinoma (ESCC). High expression miR-6775-3p is associated with good clinical outcomes of ESCC patients. Over-expression of miR-6775-3p inhibited tumor growth and liver metastasis of ESCC xenograft tumors. Enforced expression of miR-6775-3p inhibited ESCC cell proliferation, mi ...[more]