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MiRWalk: An online resource for prediction of microRNA binding sites.


ABSTRACT: miRWalk is an open-source platform providing an intuitive interface that generates predicted and validated miRNA-binding sites of known genes of human, mouse, rat, dog and cow. The core of miRWalk is the miRNA target site prediction with the random-forest-based approach software TarPmiR searching the complete transcript sequence including the 5'-UTR, CDS and 3'-UTR. Moreover, it integrates results other databases with predicted and validated miRNA-target interactions. The focus is set on a modular design and extensibility as well as a fast update cycle. The database is available using Python, MySQL and HTML/Javascript Database URL: http://mirwalk.umm.uni-heidelberg.de.

SUBMITTER: Sticht C 

PROVIDER: S-EPMC6193719 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature

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miRWalk: An online resource for prediction of microRNA binding sites.

Sticht Carsten C   De La Torre Carolina C   Parveen Alisha A   Gretz Norbert N  

PloS one 20181018 10


miRWalk is an open-source platform providing an intuitive interface that generates predicted and validated miRNA-binding sites of known genes of human, mouse, rat, dog and cow. The core of miRWalk is the miRNA target site prediction with the random-forest-based approach software TarPmiR searching the complete transcript sequence including the 5'-UTR, CDS and 3'-UTR. Moreover, it integrates results other databases with predicted and validated miRNA-target interactions. The focus is set on a modul  ...[more]

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