Ontology highlight
ABSTRACT:
SUBMITTER: Yang M
PROVIDER: S-EPMC6196232 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Yang Mingwang M Fan Jiangli J Du Jianjun J Long Saran S Wang Jia J Peng Xiaojun X
Frontiers in chemistry 20181015
Formaldehyde (FA), a highly reactive carbonyl species, plays significant role in physiological and pathological functions. However, elevated FA will lead to cognitive impairments, memory loss and various neurodegenerative diseases due to its potent DNA and protein cross-linking mechanisms. In this work, a fluorescence probe, <b>BD-CHO</b>, based on benz-2-oxa-1, 3- diazole (<b>BD</b>) skeleton, was designed and synthesized for detection of FA via Aza-Cope reaction with high selectivity and large ...[more]