Ontology highlight
ABSTRACT:
SUBMITTER: Chen S
PROVIDER: S-EPMC6201789 | biostudies-literature | 2018 Nov
REPOSITORIES: biostudies-literature
Chen Shuning S Liu Yujiao Y Zhu Shenyin S Chen Chunyan C Xie Wan W Xiao Linlin L Zhu Yi Y Hao Lan L Wang Zhigang Z Sun Jiangchuan J Chang Shufang S
Drug delivery 20181101 1
Chemotherapy and photo-sonodynamic therapy (PSDT) can be combined through drug delivery nano-platforms to enhance the anti-tumor efficacy, however, which is limited by hypoxia in tumor, thereby causing chemotherapy resistance. Perfluoropentane (PFP) has the ability to carry oxygen and to enhance ultrasound or photoacoustic imaging after vaporization. Herein, we constructed a kind of nanoparticles (PTX/ICG and oxygen loaded PLGA nanoparticles (PIO_NPs)), which had PFP core carrying oxygen and PLG ...[more]