Ontology highlight
ABSTRACT:
SUBMITTER: Zupin L
PROVIDER: S-EPMC6202264 | biostudies-literature | 2019 Sep
REPOSITORIES: biostudies-literature
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 20180320 17
<b>Introduction:</b> Human Beta Defensin-1 (hBD-1) is a component of the innate immune system, the first line of defence against pathogens, already reported as involved in the susceptibility to HIV-1 infection and HIV-1 mother-to-child transmission (MTCT) in different populations. We investigated the role of <i>DEFB1</i> gene (encoding for hBD-1) functional polymorphisms in the susceptibility to HIV-1 MTCT in a population from Zambia. <b>Methods:</b> Four selected polymorphisms within <i>DEFB1</ ...[more]