YHMI: a web tool to identify histone modifications and histone/chromatin regulators from a gene list in yeast.

ABSTRACT: Post-translational modifications of histones (e.g. acetylation, methylation, phosphorylation and ubiquitination) play crucial roles in regulating gene expression by altering chromatin structures and creating docking sites for histone/chromatin regulators. However, the combination patterns of histone modifications, regulatory proteins and their corresponding target genes remain incompletely understood. Therefore, it is advantageous to have a tool for the enrichment/depletion analysis of histone modifications and histone/chromatin regulators from a gene list. Many ChIP-chip/ChIP-seq datasets of histone modifications and histone/chromatin regulators in yeast can be found in the literature. Knowing the needs and having the data motivate us to develop a web tool, called Yeast Histone Modificati

SUBMITTER: Wu WS 

PROVIDER: S-EPMC6204766 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature