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Evaluation system and web infrastructure for the second cryo-EM model challenge.

ABSTRACT: An evaluation system and a web infrastructure were developed for the second cryo-EM model challenge. The evaluation system includes tools to validate stereo-chemical plausibility of submitted models, check their fit to the corresponding density maps, estimate their overall and per-residue accuracy, and assess their similarity to reference cryo-EM or X-ray structures as well as other models submitted in this challenge. The web infrastructure provides a convenient interface for analyzing models at different levels of detail. It includes interactively sortable tables of evaluation scores for different subsets of models and different sublevels of structure organization, and a suite of visualization tools facilitating model analysis. The results are publicly accessible at http://model-compare.emdatabank.org.

SUBMITTER: Kryshtafovych A

PROVIDER: S-EPMC6205695 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature

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Evaluation system and web infrastructure for the second cryo-EM model challenge.

Kryshtafovych Andriy A Adams Paul D PD Lawson Catherine L CL Chiu Wah W

Journal of structural biology 20180712 1

An evaluation system and a web infrastructure were developed for the second cryo-EM model challenge. The evaluation system includes tools to validate stereo-chemical plausibility of submitted models, check their fit to the corresponding density maps, estimate their overall and per-residue accuracy, and assess their similarity to reference cryo-EM or X-ray structures as well as other models submitted in this challenge. The web infrastructure provides a convenient interface for analyzing models at ...[more]

PMID: 30017700

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