Ontology highlight
ABSTRACT:
SUBMITTER: DiMaio F
PROVIDER: S-EPMC3690725 | biostudies-literature | 2013 Jun
REPOSITORIES: biostudies-literature
DiMaio Frank F Zhang Junjie J Chiu Wah W Baker David D
Protein science : a publication of the Protein Society 20130601 6
An increasing number of cryo-electron microscopy (cryo-EM) density maps are being generated with suitable resolution to trace the protein backbone and guide sidechain placement. Generating and evaluating atomic models based on such maps would be greatly facilitated by independent validation metrics for assessing the fit of the models to the data. We describe such a metric based on the fit of atomic models with independent test maps from single particle reconstructions not used in model refinemen ...[more]