Childhood asthma is associated with COPD and known asthma variants in COPDGene: a genome-wide association study.
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ABSTRACT:
SUBMITTER: Hayden LP
PROVIDER: S-EPMC6206739 | biostudies-literature | 2018 Oct
REPOSITORIES: biostudies-literature
Publications
Childhood asthma is associated with COPD and known asthma variants in COPDGene: a genome-wide association study.
Hayden Lystra P LP Cho Michael H MH Raby Benjamin A BA Beaty Terri H TH Silverman Edwin K EK Hersh Craig P CP
Respiratory research 20181029 1
<h4>Background</h4>Childhood asthma is strongly influenced by genetics and is a risk factor for reduced lung function and chronic obstructive pulmonary disease (COPD) in adults. This study investigates self-reported childhood asthma in adult smokers from the COPDGene Study. We hypothesize that childhood asthma is associated with decreased lung function, increased risk for COPD, and that a genome-wide association study (GWAS) will show association with established asthma variants.<h4>Methods</h4> ...[more]
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