Ontology highlight
ABSTRACT:
SUBMITTER: Brate J
PROVIDER: S-EPMC6206976 | biostudies-literature | 2018 Oct
REPOSITORIES: biostudies-literature
Bråte Jon J Neumann Ralf S RS Fromm Bastian B Haraldsen Arthur A B AAB Tarver James E JE Suga Hiroshi H Donoghue Philip C J PCJ Peterson Kevin J KJ Ruiz-Trillo Iñaki I Grini Paul E PE Shalchian-Tabrizi Kamran K
Current biology : CB 20181011 20
The emergence of multicellular animals was associated with an increase in phenotypic complexity and with the acquisition of spatial cell differentiation and embryonic development. Paradoxically, this phenotypic transition was not paralleled by major changes in the underlying developmental toolkit and regulatory networks. In fact, most of these systems are ancient, established already in the unicellular ancestors of animals [1-5]. In contrast, the Microprocessor protein machinery, which is essent ...[more]