Ontology highlight
ABSTRACT:
SUBMITTER: Grabowski P
PROVIDER: S-EPMC6210221 | biostudies-literature | 2018 Nov
REPOSITORIES: biostudies-literature
Grabowski Piotr P Kustatscher Georg G Rappsilber Juri J
Molecular & cellular proteomics : MCP 20180724 11
Genes are often coexpressed with their genomic neighbors, even if these are functionally unrelated. For small expression changes driven by genetic variation within the same cell type, non-functional mRNA coexpression is not propagated to the protein level. However, it is unclear if protein levels are also buffered against any non-functional mRNA coexpression accompanying large, regulated changes in the gene expression program, such as those occurring during cell differentiation. Here, we address ...[more]