Ontology highlight
ABSTRACT:
SUBMITTER: Joseph-Mathurin N
PROVIDER: S-EPMC6215983 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Alzheimer's & dementia (Amsterdam, Netherlands) 20180927
<h4>Introduction</h4><sup>18</sup>F-fluorodeoxyglucose (FDG) positron emission tomography (PET) is commonly used to estimate neuronal injury in Alzheimer's disease (AD). Here, we evaluate the utility of dynamic PET measures of perfusion using <sup>11</sup>C-Pittsburgh compound B (PiB) to estimate neuronal injury in comparison to FDG PET.<h4>Methods</h4>FDG, early frames of PiB images, and relative PiB delivery rate constants (PiB-R1) were obtained from 110 participants from the Dominantly Inheri ...[more]