Unknown

Dataset Information

0

The EnvZ-OmpR Two-Component Signaling System Is Inactivated in a Mutant Devoid of Osmoregulated Periplasmic Glucans in Dickeya dadantii.


ABSTRACT: Osmoregulated periplasmic glucans (OPGs) are general constituents of alpha-, beta-, and gamma-Proteobacteria. This polymer of glucose is required for full virulence of many pathogens including Dickeya dadantii (D. dadantii). The phytopathogenic enterobacterium D. dadantii causes soft-rot disease in a wide range of plants. An OPG-defective mutant is impaired in environment sensing. We previously demonstrated that (i) fluctuation of OPG concentration controlled the activation level of the RcsCDB system, and (ii) RcsCDB along with EnvZ/OmpR controlled the mechanism of OPG succinylation. These previous data lead us to explore whether OPGs are required for other two-component systems. In this study, we demonstrate that inactivation of the EnvZ/OmpR system in an OPG-defective mutant restores full synthesis of pectinase but only partial virulence. Unlike for the RcsCDB system, the EnvZ-OmpR system is not controlled by OPG concentration but requires OPGs for proper activation.

SUBMITTER: Caby M 

PROVIDER: S-EPMC6218677 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature

altmetric image

Publications

The EnvZ-OmpR Two-Component Signaling System Is Inactivated in a Mutant Devoid of Osmoregulated Periplasmic Glucans in <i>Dickeya dadantii</i>.

Caby Marine M   Bontemps-Gallo Sébastien S   Gruau Peggy P   Delrue Brigitte B   Madec Edwige E   Lacroix Jean-Marie JM  

Frontiers in microbiology 20181030


Osmoregulated periplasmic glucans (OPGs) are general constituents of alpha-, beta-, and gamma-Proteobacteria. This polymer of glucose is required for full virulence of many pathogens including <i>Dickeya dadantii (D. dadantii)</i>. The phytopathogenic enterobacterium <i>D. dadantii</i> causes soft-rot disease in a wide range of plants. An OPG-defective mutant is impaired in environment sensing. We previously demonstrated that (i) fluctuation of OPG concentration controlled the activation level o  ...[more]

Similar Datasets

| S-EPMC4726272 | biostudies-literature
| S-EPMC95213 | biostudies-literature
| S-EPMC2981204 | biostudies-literature
| S-EPMC7013093 | biostudies-literature
| S-EPMC3160321 | biostudies-literature
| S-EPMC2727453 | biostudies-literature
| S-EPMC7192543 | biostudies-literature
| S-EPMC2761842 | biostudies-literature
| S-EPMC93837 | biostudies-literature
| S-EPMC5237114 | biostudies-literature