Ontology highlight
ABSTRACT:
SUBMITTER: Shaw LM
PROVIDER: S-EPMC6222032 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Shaw Leslie M LM Waligorska Teresa T Fields Leona L Korecka Magdalena M Figurski Michal M Trojanowski John Q JQ Eichenlaub Udo U Wahl Simone S Quan Marian M Pontecorvo Michael J MJ Lachno D Richard DR Talbot Jayne A JA Andersen Scott W SW Siemers Eric R ER Dean Robert A RA
Alzheimer's & dementia (Amsterdam, Netherlands) 20180811
<h4>Introduction</h4>An Elecsys® Amyloid β (Aβ [1-42]) immunoassay cutoff for classification of patients with Alzheimer's disease was investigated.<h4>Methods</h4>Cerebrospinal fluid samples collected from patients with mild-to-moderate Alzheimer's disease were analyzed by Elecsys® immunoassays: (1) Aβ (1-42), (2) total tau, and (3) phosphorylated tau. Cutoffs (Aβ [1-42] and ratios with tau) were estimated by method comparison between AlzBio3 (<i>n</i> = 206), mixture modeling (<i>n</i> = 216), ...[more]