Ontology highlight
ABSTRACT:
SUBMITTER: Chen Q
PROVIDER: S-EPMC6222736 | biostudies-literature | 2018 Sep
REPOSITORIES: biostudies-literature
Chen Qianqian Q Jiang Panli P Guo Mengping M Yang Jianxin J
Molecules (Basel, Switzerland) 20180925 10
A series of novel benzofuran derivatives containing biaryl moiety were designed and synthesized by the Suzuki cross-coupling reactions. The reactions, performed in the presence of K₂CO₃, EtOH/H₂O and Pd(II) complex as catalyst, gave the corresponding products in good to excellent yields. The methodology allows the facile production of heterobiaryl compounds, a unique architectural motif that is ubiquitous in medicinal chemistry. ...[more]