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Chemical Constituents from Scindapsus officinalis (Roxb.) Schott. and Their Anti?Inflammatory Activities.

ABSTRACT: One new monoterpene glycoside (1), one new phenyl glycoside (2), one new caffeoyl derivative (3), were isolated from Scindapsus officinalis (Roxb.) Schott., along with four known compounds (4?7). Structures of the isolated compounds were elucidated by extensive analysis of spectroscopic data, especially 2D NMR data and comparison with literatures. All isolates were evaluated for anti-inflammatory activity against nitric oxide (NO) production in vitro. Compounds 3 and 7 exhibited moderate inhibitory effects on NO production with IC50 values of 12.2 ± 0.8 and 18.9 ± 0.3 ?M, respectively.

SUBMITTER: Dong H 

PROVIDER: S-EPMC6222759 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature

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Chemical Constituents from <i>Scindapsus officinalis</i> (Roxb.) Schott. and Their Anti⁻Inflammatory Activities.

Dong Hongjing H   Geng Yanling Y   Wang Xueyong X   Song Xiangyun X   Wang Xiao X   Yu Jinqian J  

Molecules (Basel, Switzerland) 20181009 10

One new monoterpene glycoside (<b>1</b>), one new phenyl glycoside (<b>2</b>), one new caffeoyl derivative (<b>3</b>), were isolated from <i>Scindapsus officinalis</i> (Roxb.) Schott., along with four known compounds (<b>4⁻7</b>). Structures of the isolated compounds were elucidated by extensive analysis of spectroscopic data, especially 2D NMR data and comparison with literatures. All isolates were evaluated for anti-inflammatory activity against nitric oxide (NO) production in vitro. Compounds  ...[more]

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