Ontology highlight
ABSTRACT:
SUBMITTER: Gao YT
PROVIDER: S-EPMC6225319 | biostudies-literature | 2018 Sep
REPOSITORIES: biostudies-literature
Gao Yu-Ting YT Jin Xiao-Yang XY Liu Qi Q Liu An-Di AD Cheng Liang L Wang Dong D Liu Li L
Molecules (Basel, Switzerland) 20180905 9
An ammonium iodide/hydrogen peroxide-mediated intramolecular oxidative amination of 3-aminoalkyl-2-oxindoles was achieved, affording the corresponding 3,2'-pyrrolidinyl spirooxindoles and their 6- or 7-membered analogous in moderate to high yields. This metal-free procedure features very mild reaction conditions, non-toxicity and easily handled hydrogen peroxide as a clean oxidant. ...[more]