Ontology highlight
ABSTRACT:
SUBMITTER: Marioni RE
PROVIDER: S-EPMC6225560 | biostudies-literature | 2018 Nov
REPOSITORIES: biostudies-literature
Marioni Riccardo E RE Belsky Daniel W DW Deary Ian J IJ Wagner Wolfgang W
Clinical epigenetics 20181108 1
Evaluation of biological age, as opposed to chronological age, is of high relevance for interventions to increase healthy ageing. Highly reproducible age-associated DNA methylation (DNAm) changes can be integrated into algorithms for epigenetic age predictions. These predictors have mostly been trained to correlate with chronological age, but they are also indicative for biological ageing. For example, accelerated epigenetic age of blood is associated with higher risk of all-cause mortality in l ...[more]