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Isothiocyanates: Translating the Power of Plants to People.

ABSTRACT: Isothiocyanates from cruciferous vegetables have been studied extensively in cells and in animals for their disease preventive and therapeutic effects. However, translating their utility to human populations has been both limited and challenging. Herein, clinical trials employing two isothiocyanates, sulforaphane (SFN; 1-isothiocyanato-4-(methylsulfinyl) butane) and phenethyl isothiocyanate (PEITC; 2-isothiocyanatoethylbenzene) that are isolated principally from broccoli and watercress, respectively, are summarized and discussed. Both of these compounds have been used in small human clinical trials, either within food matrices or as single agents, against a variety of diseases ranging from cancer to autism. Results suggest an opportunity to incorporate them, or more likely preparations derived from their source plants, into larger human disease mitigation efforts. The context for the applications of these compounds and plants in evidence-based food and nutritional policy is also evaluated.

SUBMITTER: Palliyaguru DL

PROVIDER: S-EPMC6226005 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature

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Isothiocyanates: Translating the Power of Plants to People.

Palliyaguru Dushani L DL Yuan Jian-Min JM Kensler Thomas W TW Fahey Jed W JW

Molecular nutrition & food research 20180326 18

Isothiocyanates from cruciferous vegetables have been studied extensively in cells and in animals for their disease preventive and therapeutic effects. However, translating their utility to human populations has been both limited and challenging. Herein, clinical trials employing two isothiocyanates, sulforaphane (SFN; 1-isothiocyanato-4-(methylsulfinyl) butane) and phenethyl isothiocyanate (PEITC; 2-isothiocyanatoethylbenzene) that are isolated principally from broccoli and watercress, respecti ...[more]

PMID: 29468815

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Project description:Electric production from geothermal energy is still little exploited compared to its large potential and to the World renewable energy production from other sources. Some countries have exploited this energy source in order to enhance their transition to renewables. Today the largest geothermal energy producers in the world are New Zealand, U.S.A, Mexico, Philippines, Italy, Iceland, and, more recently, Turkey (Geothermal, 2012). Differently from other renewable sources, geothermal energy produces impacts on the environment that are very site-specific because of the nature of the resource and its geological characteristics Bravi et al.,2010; Parisi et al.,2013. In the same way, the atmospheric emissions associated to the activity of geothermal power plants for electric or heat production (mainly CO2, H2S, NH3, Hg, CH4) are also site-specific. In fact, due to technological and geographical differences among the geothermal installations operating all over the World, it is quite impossible to identify and attribute typical emission patterns, to perform forecasts valid for multiple sites or to collect universal data. Furthermore, it is virtually impossible the comparison among technologies located in different regions or countries. Definitively, inventories of primary data, as accurate and complete as possible, are essential to correctly evaluate the peculiarities of geo-thermoelectric energy production Parisi et al.,2018. Data reported here try to fill the gap in respect to the Italian situation. To this end, a complete survey of the atmospheric emissions from all the geothermal power plants in operation in the Tuscany Region is performed. In addition to data reporting, also some statistical analysis is performed to process data and to operate a further level of simplification which averages the emissions on the basis of geothermal sub-areas. The data collected is related to the research article "Life cycle assessment of atmospheric emission profiles of the Italian geothermal power plants" Parisi et al.,2019.

Dataset Information

Isothiocyanates: Translating the Power of Plants to People.

Publications

Isothiocyanates: Translating the Power of Plants to People.

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