Embryology of the Parathyroid Glands.
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ABSTRACT:
SUBMITTER: Peissig K
PROVIDER: S-EPMC6226091 | biostudies-literature | 2018 Dec
REPOSITORIES: biostudies-literature
Publications
Embryology of the Parathyroid Glands.
Peissig Kristen K Condie Brian G BG Manley Nancy R NR
Endocrinology and metabolism clinics of North America 20181201 4
The parathyroid glands are essential for regulating calcium homeostasis in the body. The genetic programs that control parathyroid fate specification, morphogenesis, differentiation, and survival are only beginning to be delineated, but are all centered around a key transcription factor, GCM2. Mutations in the Gcm2 gene as well as in several other genes involved in parathyroid organogenesis have been found to cause parathyroid disorders in humans. Therefore, understanding the normal development ...[more]
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