Ontology highlight
ABSTRACT:
SUBMITTER: Abs E
PROVIDER: S-EPMC6226614 | biostudies-literature | 2018 Nov
REPOSITORIES: biostudies-literature
Abs Elisabeth E Poorthuis Rogier B RB Apelblat Daniella D Muhammad Karzan K Pardi M Belen MB Enke Leona L Kushinsky Dahlia D Pu De-Lin DL Eizinger Max Ferdinand MF Conzelmann Karl-Klaus KK Spiegel Ivo I Letzkus Johannes J JJ
Neuron 20180927 3
A wealth of data has elucidated the mechanisms by which sensory inputs are encoded in the neocortex, but how these processes are regulated by the behavioral relevance of sensory information is less understood. Here, we focus on neocortical layer 1 (L1), a key location for processing of such top-down information. Using Neuron-Derived Neurotrophic Factor (NDNF) as a selective marker of L1 interneurons (INs) and in vivo 2-photon calcium imaging, electrophysiology, viral tracing, optogenetics, and a ...[more]