Ontology highlight
ABSTRACT:
SUBMITTER: Ma M
PROVIDER: S-EPMC7459332 | biostudies-literature | 2020 Aug
REPOSITORIES: biostudies-literature
Ma Ming M Futia Gregory L GL de Souza Fabio M Simoes FMS Ozbay Baris N BN Llano Isabel I Gibson Emily A EA Restrepo Diego D
Nature communications 20200831 1
The cerebellum plays a crucial role in sensorimotor and associative learning. However, the contribution of molecular layer interneurons (MLIs) to these processes is not well understood. We used two-photon microscopy to study the role of ensembles of cerebellar MLIs in a go-no go task where mice obtain a sugar water reward if they lick a spout in the presence of the rewarded odorant and avoid a timeout when they refrain from licking for the unrewarded odorant. In naive animals the MLI responses d ...[more]