Ontology highlight
ABSTRACT:
SUBMITTER: Strisciuglio T
PROVIDER: S-EPMC6232354 | biostudies-literature | 2018 Oct
REPOSITORIES: biostudies-literature
Strisciuglio Teresa T Franco Danilo D Di Gioia Giuseppe G De Biase Chiara C Morisco Carmine C Trimarco Bruno B Barbato Emanuele E
Cardiovascular diagnosis and therapy 20181001 5
Cardiovascular genomic consists in the identification of polymorphic genes responsible for the susceptibility to cardiovascular disease including coronary artery disease (CAD). Genes involved in platelet activation and aggregation play a key role in the predisposition to CAD. A considerable inter-variability of platelet response to agonists and to drugs exists and in particular the hyper-reactivity phenotype seems to be heritable. Besides glycoproteins and receptors expressed on platelets surfac ...[more]