Ontology highlight
ABSTRACT:
SUBMITTER: Giometto A
PROVIDER: S-EPMC6233111 | biostudies-literature | 2018 Nov
REPOSITORIES: biostudies-literature
Giometto Andrea A Nelson David R DR Murray Andrew W AW
Proceedings of the National Academy of Sciences of the United States of America 20181023 45
Microbial populations often assemble in dense populations in which proliferating individuals exert mechanical forces on the nearby cells. Here, we use yeast strains whose doubling times depend differently on temperature to show that physical interactions among cells affect the competition between different genotypes in growing yeast colonies. Our experiments demonstrate that these physical interactions have two related effects: they cause the prolonged survival of slower-growing strains at the a ...[more]