Ontology highlight
ABSTRACT:
SUBMITTER: Gulick AM
PROVIDER: S-EPMC6235721 | biostudies-literature | 2018 Nov
REPOSITORIES: biostudies-literature
Gulick Andrew M AM Aldrich Courtney C CC
Natural product reports 20181101 11
Covering: up to early 2018 The Nonribosomal Peptide Synthetases (NRPSs) and Polyketide Synthases (PKSs) are families of modular enzymes that produce a tremendous diversity of natural products, with antibacterial, antifungal, immunosuppressive, and anticancer activities. Both enzymes utilize a fascinating modular architecture in which the synthetic intermediates are covalently attached to a peptidyl- or acyl-carrier protein that is delivered to catalytic domains for natural product elongation, mo ...[more]