Extended spectrum beta-lactamase mediated resistance in carriage and clinical gram-negative ESKAPE bacteria: a comparative study between a district and tertiary hospital in South Africa.

ABSTRACT:

Background

Gram-negative ESKAPE bacteria are increasingly implicated in several difficult-to-treat infections in developed and developing countries. They are listed by the World Health Organization as resistant bacteria of critical priority in research.

Objectives

To determine the risk factors, prevalence, phenotypic profiles, genetic diversity and clonal relatedness of extended-spectrum β-lactamase (ESBL)-producing multi-drug resistant (MDR) Gram-negative ESKAPE bacteria in the faecal carriage and clinical samples from patients in an urban, tertiary and a rural, district hospital in uMgungundlovu District, KwaZulu-Natal, South Africa.

Methods

This study took place in a district and tertiary hospital during a two-months period from May to June 2017 in uMgungundlovu di

SUBMITTER: Founou RC 

PROVIDER: S-EPMC6237030 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature