Ontology highlight
ABSTRACT:
SUBMITTER: Cakir B
PROVIDER: S-EPMC6237470 | biostudies-literature | 2018 Oct
REPOSITORIES: biostudies-literature
Cakir Bertan B Liegl Raffael R Hellgren Gunnel G Lundgren Pia P Sun Ye Y Klevebro Susanna S Löfqvist Chatarina C Mannheimer Clara C Cho Steve S Poblete Alexander A Duran Rubi R Hallberg Boubou B Canas Jorge J Lorenz Viola V Liu Zhi-Jian ZJ Sola-Visner Martha C MC Smith Lois Eh LE Hellström Ann A
JCI insight 20181004 19
Retinopathy of prematurity (ROP) is characterized by abnormal retinal neovascularization in response to vessel loss. Platelets regulate angiogenesis and may influence ROP progression. In preterm infants, we assessed ROP and correlated with longitudinal postnatal platelet counts (n = 202). Any episode of thrombocytopenia (<100 × 109/l) at ≥30 weeks postmenstrual age (at onset of ROP) was independently associated with severe ROP, requiring treatment. Infants with severe ROP also had a lower weekly ...[more]