Ontology highlight
ABSTRACT:
SUBMITTER: Muenzner JK
PROVIDER: S-EPMC6237557 | biostudies-literature | 2018 Dec
REPOSITORIES: biostudies-literature
Muenzner Julienne K JK Kunze Philipp P Lindner Pablo P Polaschek Sandra S Menke Kira K Eckstein Markus M Geppert Carol I CI Chanvorachote Pithi P Baeuerle Tobias T Hartmann Arndt A Schneider-Stock Regine R
Journal of cellular and molecular medicine 20181002 12
Hepatocellular carcinoma (HCC) is one of the most common causes for cancer-related death worldwide with rapidly increasing incidence and mortality rates. As for other types of cancers, also in HCC cancer stem cells (CSCs) are thought to be responsible for tumour initiation, progression and therapy failure. However, as rare subpopulations of tumour tissue, CSCs are difficult to isolate, thus making the development of suitable and reliable model systems necessary. In our study, we generated HepG2 ...[more]