Ontology highlight
ABSTRACT:
SUBMITTER: Li Y
PROVIDER: S-EPMC7744694 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Frontiers in pharmacology 20201203
Hepatocellular carcinoma (HCC) is the most common type of primary liver cancer. <i>Cancer</i> stem cells (CSCs) are a rare population with self-renewal and multipotent differentiation capacity, and reside among the more differentiated cancer cells. CSCs are associated with tumor recurrence, drug resistance and poor prognosis. The aim of this study was to determine the efficacy of napabucasin against HCC and elucidate the underlying molecular mechanisms. Napabucasin significantly decreased the vi ...[more]