Ontology highlight
ABSTRACT:
SUBMITTER: Balatti V
PROVIDER: S-EPMC6238191 | biostudies-literature | 2018 Nov
REPOSITORIES: biostudies-literature
Balatti Veronica V Tomasello Luisa L Rassenti Laura Z LZ Veneziano Dario D Nigita Giovanni G Wang Huan-You HY Thorson John A JA Kipps Thomas J TJ Pekarsky Yuri Y Croce Carlo M CM
Blood 20180921 20
Chronic lymphocytic leukemia (CLL) is the most common adult leukemia. It is characterized by the accumulation of CD19<sup>+</sup>/CD5<sup>+</sup> lymphocytes and can have variable outcomes. Richter syndrome (RS) is a lethal complication in CLL patients that results in aggressive B-cell lymphomas, and there are no tests to predict its occurrence. Because alterations in microRNA expression can predict the development and progression of several cancers, we investigated whether dysregulation of spec ...[more]