Ontology highlight
ABSTRACT:
SUBMITTER: Romarowski A
PROVIDER: S-EPMC6240301 | biostudies-literature | 2018 Nov
REPOSITORIES: biostudies-literature
Romarowski Ana A Velasco Félix Ángel G ÁG Torres Rodríguez Paulina P Gervasi María G MG Xu Xinran X Luque Guillermina M GM Contreras-Jiménez Gastón G Sánchez-Cárdenas Claudia C Ramírez-Gómez Héctor V HV Krapf Diego D Visconti Pablo E PE Krapf Dario D Guerrero Adán A Darszon Alberto A Buffone Mariano G MG
Journal of cell science 20181108 21
Filamentous actin (F-actin) is a key factor in exocytosis in many cell types. In mammalian sperm, acrosomal exocytosis (denoted the acrosome reaction or AR), a special type of controlled secretion, is regulated by multiple signaling pathways and the actin cytoskeleton. However, the dynamic changes of the actin cytoskeleton in live sperm are largely not understood. Here, we used the powerful properties of SiR-actin to examine actin dynamics in live mouse sperm at the onset of the AR. By using a c ...[more]