Ontology highlight
ABSTRACT:
SUBMITTER: Morita M
PROVIDER: S-EPMC6242345 | biostudies-literature | 2018 May
REPOSITORIES: biostudies-literature
Morita Maho M Hao Yue Y Jokela Jouni K JK Sardar Debosmita D Lin Zhenjian Z Sivonen Kaarina K Nair Satish K SK Schmidt Eric W EW
Journal of the American Chemical Society 20180501 19
Prenylation is a widespread modification that improves the biological activities of secondary metabolites. This reaction also represents a key modification step in biosyntheses of cyanobactins, a family of ribosomally synthesized and post-translationally modified peptides (RiPPs) produced by cyanobacteria. In cyanobactins, amino acids are commonly isoprenylated by ABBA prenyltransferases that use C<sub>5</sub> donors. Notably, mass spectral analysis of piricyclamides from a fresh-water cyanobact ...[more]