Ontology highlight
ABSTRACT:
SUBMITTER: Du Z
PROVIDER: S-EPMC6244186 | biostudies-literature | 2018 Nov
REPOSITORIES: biostudies-literature
Scientific data 20181120
Pluripotent stem cells hold great investigative potential for developmental biology and regenerative medicine. Recent studies suggest that long noncoding RNAs (lncRNAs) may function as key regulators of the maintenance and the lineage differentiation of stem cells. However, the underlying mechanisms by which lncRNAs affect the reprogramming process of somatic cells into pluripotent cells remain largely unknown. Using fibroblasts and induced pluripotent stem cells (iPSCs) at different stages of r ...[more]