Ontology highlight
ABSTRACT:
SUBMITTER: Liu YL
PROVIDER: S-EPMC6244932 | biostudies-literature | 2018 Nov
REPOSITORIES: biostudies-literature
Liu Ying L YL Zamarin Dmitriy D
Current oncology reports 20181113 12
<h4>Purpose of review</h4>Immune checkpoint blockade targeting PD-1 and PD-L1 improves immune recognition of tumor cells but had only modest success in gynecological cancers as monotherapy. Growing focus has been placed on combination immunotherapy strategies to overcome this resistance, and this review serves to discuss some of the most promising studies in gynecological cancers.<h4>Recent findings</h4>PD-1- and PD-L1-targeting antibodies are being combined with many novel agents including anti ...[more]