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KMgene: a unified R package for gene-based association analysis for complex traits.

ABSTRACT: Summary:In this report, we introduce an R package KMgene for performing gene-based association tests for familial, multivariate or longitudinal traits using kernel machine (KM) regression under a generalized linear mixed model framework. Extensive simulations were performed to evaluate the validity of the approaches implemented in KMgene. Availability and implementation:http://cran.r-project.org/web/packages/KMgene. Supplementary information:Supplementary data are available at Bioinformatics online.

SUBMITTER: Yan Q

PROVIDER: S-EPMC6246171 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature

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KMgene: a unified R package for gene-based association analysis for complex traits.

Yan Qi Q Fang Zhou Z Chen Wei W

Bioinformatics (Oxford, England) 20180601 12

<h4>Summary</h4>In this report, we introduce an R package KMgene for performing gene-based association tests for familial, multivariate or longitudinal traits using kernel machine (KM) regression under a generalized linear mixed model framework. Extensive simulations were performed to evaluate the validity of the approaches implemented in KMgene.<h4>Availability and implementation</h4>http://cran.r-project.org/web/packages/KMgene.<h4>Supplementary information</h4>Supplementary data are available ...[more]

PMID: 29438558

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