Ontology highlight
ABSTRACT:
SUBMITTER: Ben-David E
PROVIDER: S-EPMC6251971 | biostudies-literature | 2017 Jun
REPOSITORIES: biostudies-literature
Ben-David Eyal E Burga Alejandro A Kruglyak Leonid L
Science (New York, N.Y.) 20170511 6342
Selfish genetic elements spread in natural populations and have an important role in genome evolution. We discovered a selfish element causing embryonic lethality in crosses between wild strains of the nematode <i>Caenorhabditis elegans</i> The element is made up of <i>sup-35</i>, a maternal-effect toxin that kills developing embryos, and <i>pha-1</i>, its zygotically expressed antidote. <i>pha-1</i> has long been considered essential for pharynx development on the basis of its mutant phenotype, ...[more]