Ontology highlight
ABSTRACT:
SUBMITTER: Yizhar-Barnea O
PROVIDER: S-EPMC6255903 | biostudies-literature | 2018 Nov
REPOSITORIES: biostudies-literature
Yizhar-Barnea Ofer O Valensisi Cristina C Jayavelu Naresh Doni ND Kishore Kamal K Andrus Colin C Koffler-Brill Tal T Ushakov Kathy K Perl Kobi K Noy Yael Y Bhonker Yoni Y Pelizzola Mattia M Hawkins R David RD Avraham Karen B KB
Scientific reports 20181126 1
The inner ear is a complex structure responsible for hearing and balance, and organ pathology is associated with deafness and balance disorders. To evaluate the role of epigenomic dynamics, we performed whole genome bisulfite sequencing at key time points during the development and maturation of the mouse inner ear sensory epithelium (SE). Our single-nucleotide resolution maps revealed variations in both general characteristics and dynamics of DNA methylation over time. This allowed us to predic ...[more]