Ontology highlight
ABSTRACT:
SUBMITTER: Tan HJ
PROVIDER: S-EPMC6256173 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Tan Hui-Jun HJ Deng Mei M Qiu Jian-Wu JW Wu Jun-Feng JF Song Yuan-Zong YZ
Frontiers in pediatrics 20181120
Sodium taurocholate cotransporting polypeptide (NTCP) is a carrier protein encoded by the human <i>SLC10A1</i> gene, acting as the principal transporter of conjugated bile salts from the plasma into hepatocytes. Although NTCP was cloned as early as in 1994 and its function has been studied extensively, clinical description of NTCP deficiency remains rather limited thus far. The patients in this paper were 2 female monozygotic twins, who were referred to our hospital at the age 2 years with the c ...[more]