Ontology highlight
ABSTRACT:
SUBMITTER: Santos ML
PROVIDER: S-EPMC6259155 | biostudies-literature | 2011 Jan
REPOSITORIES: biostudies-literature
Santos Marcelo L ML Toyama Daniela O DO Oliveira Simone C B SC Cotrim Camila A CA Diz-Filho Eduardo B S EB Fagundes Fábio H R FH Soares Veronica C G VC Aparicio Ricardo R Toyama Marcos H MH
Molecules (Basel, Switzerland) 20110118 1
In this work we have characterized the action of the naringin, a flavonoid found in grapefruit and known for its various pharmacological effects, which include antioxidant blood lipid lowering and anticancer activity, on the structure and biochemical activities of a secretory phospholipase A (sPLA2) from Crotalus durissus cascavella, an important protein involved in the releasinge of arachidonic acid in phospholipid membranes. sPLA2 was incubated with naringin (mol:mol) at 37 °C and a discrete r ...[more]