Ontology highlight
ABSTRACT:
SUBMITTER: Moharam BA
PROVIDER: S-EPMC6259456 | biostudies-literature | 2010 Nov
REPOSITORIES: biostudies-literature
Moharam Bushra Abdulkarim BA Jantan Ibrahim I Jalil Juriyati J Shaari Khozirah K
Molecules (Basel, Switzerland) 20101103 11
Phylligenine, together with quebrachitol, stigmasterol and two aporphine alkaloids--oxoputerine and liriodenine--were isolated from the twigs of Mitrephora vulpina C.E.C. Fisch. They were evaluated for their ability to inhibit platelet activating factor (PAF) receptor binding to rabbit platelets using 3H-PAF as a ligand and their antiplatelet aggregation effect in human whole blood induced by arachidonic acid (AA), collagen and adenosine diphosphate (ADP). Of all the compounds tested, phylligeni ...[more]